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RPE cells in AMD were observed with decreased PINK1 mitophagy pathway, affecting mitophagy and increasing ROS, which induces epithelial-mesenchymal transition
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The alladium pyrithione complex is a broad-spectrum inhibitor of deubiquitinases that induces apoptosis and ferroptosis in human non-small cell lung cancer cells in part through GPX4 degradation [63]
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