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Moreover, in contrast to protein oxidation, lipid peroxidation, and cell death following Aฮฒ40 or Aฮฒ42 addition to neuronal cultures, none of these occurred with the norleucine-substituted Aฮฒ peptide (112โ114), i.e., the Met35 residue of Aฮฒ42 was hinted at as being important in the free radical associated with this neurotoxic peptide
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