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When the decision criteria or logic for transition to NSZD is not well prescribed in decision documents, but the need emerges for remedy transition to a more effective and efficient approach (e.g., when a mass removal plateau is observed), practice has generally evolved to use multiple lines-of-evidence to justify transition

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Wound healing and the vascular question In both cell systems and animal models, including rat hindlimb ischemia, corneal injury, and skin-wound models, BPC-157 has been associated with promoting healing partly through new blood vessels, with increased vessel density, enhanced Akt-eNOS signaling, and faster blood-flow recovery

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