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The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78)
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Overall, changes in SCFA-producing bacteria in the gut, and the influx of SCFAs into the blood stream, could thus have a distal effect in microglia and astrocyte functions, as well as in modifying blood–brain barrier permeability and the entrance of immune cells into the CNS (Fig
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