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Neuronal (nNOS or NOS1) and endothelial (eNOS or NOS3) are both constitutive, calcium-dependent forms of the enzyme that undergo negative feedback regulation (Stuehr 1997), in addition to regulatory phosphorylation (Dimmeler, Fleming et al
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Hypothesis 2: Adherence to a Mediterranean dietary pattern appears to influence thyroid autoimmunity—indicated by lower levels of TPOAbs and TgAbs—and may decrease systemic inflammation, subsequently improving cardiovascular outcomes
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