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Glutathione Dehydrogenase (Ascorbate) - an overview | ScienceDirect Topics
doi: 10.1016/j.bbrc.2020.08.076
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Results GSH depletion induces cell death in RPE cells To evaluate the effect of GSH depletion on the RPE cells, we used three different approaches: depletion of Cys 2 from cell culture media, treatment with buthionine sulphoximine (BSO, 1000 µM) to block de novo synthesis of GSH, or treatment with erastin (10 µM), an inhibitor of system x c − 1
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