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To test the anti-inflammatory effect of Liproxstatin-1 7- to 10-week-old WT and Gpx4 +/โIEC mice were fed a Western diet (ssniff, TD88137) with 10% fish oil (ssniff supplementation, see Table S2) for 3 months ad libitum
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The first stage is a reaction where the cytochrome P450 monooxygenase system and aldo-keto-reductase (AKR), carboxylesterases (CES), and epoxide hydrolase are involved
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