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AVETRIC (NCT04513951) examined the combination of mFOLFOXIRI, cetuximab (EGFR inhibitor), and avelumab (anti-PD-L1) in pMMR/MSS mCRC patients with wild-type RAS, and met its primary end point with median PFS of 14.1 months, a ORR of 82%, a disease control rate (DCR) of 98%, and a R0 recession rate of 21%
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The reason glutathione is commonly given by IV or injection rather than as a capsule comes down to the same problem that affects peptides generally
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