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After receiving a signal from a membrane bound receptor, the MAPK pathway activates when RAS, a GTPase, activates a phosphorylation cascade involving three kinases RAF, MEK, and ERK (180)
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However, with the application of detection technologies, such as polymerase chain reaction (PCR), next-generation sequencing (NGS), and the maturation of DNA sequencing, 7,8 researchers began to pay attention to the lung microbiome
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