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Stringent quality control using Trimmomatic v0.36 107 , in which the Illumina adapters were excised, reads were trimmed using a 4 bp sliding window with an average quality score threshold of Q15, and reads containing any ambiguous bases were removed
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Reactive oxygen species (ROS) are endogenously produced from mitochondria, cytochrome P450 metabolism, peroxisomes, and inflammatory cell activation [24,25,26]
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