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As shown in the section below, SIRT1 also catalyses a range of substrates such as NF-ΞΊB, forkhead box class O family member proteins (FOXOs), peroxisome proliferator-activated receptor Ξ³ (PPARΞ³), peroxisome proliferator-activated receptor Ξ³ coactivator 1Ξ± (PGC-1Ξ±), and P53 [338,339,340]
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