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3.1.2 Interference with arachidonic acid cascade In an lipopolysaccharide (LPS)-stimulated macrophage model, researchers found that MgIG inhibited the activation of PLA 2 in LPS-stimulated macrophages (Xie et al., 2015)
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Furthermore, elevated zonulin levels appear to be an interesting biomarker to identify those patients that are of highest risk to progress to RA, thus allowing a precision-medicine approach to target such individuals
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