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Disclosures: Moony Su: Nothing to Disclose, Olivia Matthews: Resolution Therapeutics: Employee, Resolution Therapeutics: Stock – privately held company, Mark Cant: Nothing to Disclose, Anna Hoy: Resolution Therapeutics: Employee, Resolution Therapeutics: Employee, Resolution Therapeutics: Stock – privately held company, Niya Aleksieva: Nothing to Disclose, Rachel Lopera: Nothing to Disclose, Philip Starkey Lewis: Resolution Therapeutics Ltd: Employee, Resolution Therapeutics Ltd: Stock – privately held company, Alejandro Armesilla-Diaz: Nothing to Disclose, Keith Sutton: Resolution Therapeutics: Employee, Kayleigh Thirlwell: Nothing to Disclose, Lara Campana: Resolution Therapeutics: Employee 1991 HEPATIC STELLATE CELLS FACILITATES AMMONIA DETOXIFICATION THROUGH GPT1-MEDIATED ALANINE SYNTHESIS IN HEPATOCELLULAR CARCINOMA Thi Nga Ha 1 Hyon-Seung Yi 1 Dong Wook Choi 2 , 1 Chungnam National University, 2 Korea University Background: Targeting metabolic reprogramming during the activation of hepatic stellate cells (HSCs) has recently been highlighted as an emerging strategy for mitigating hepatic diseases

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Size:10mg-Reconstituted

Glutathione-S-Transferase Inhibition by Phytochemicals The expression of certain glutathione S-transferase isoenzymes (e.g., GSTP1) is elevated in many types of cancer and is associated with the promotion of cancer development (through apoptosis inhibition and uncontrolled cell proliferation) as well as with multidrug resistance (MDR) [6,98]