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Some suggest that a "loading phase" of up to 2,000mg per day for the first few weeks can be helpful, though this should always be discussed with a healthcare provider

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This modulation ultimately leads to a suppression of the production and secretion of inflammatory cytokines, including TNF-α, IL-1β, and IL-6, thereby regulating inflammatory reactions and mitigating tissue damage in T cell-mediated autoimmune diseases, such as RA, MS, and inflammatory bowel disease (218)